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SB 223412, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
174636-32-9
C25H22N2O2
382.463
BIAVGWDGIJKWRM-FQEVSTJZSA-N
talnetant,talnetant inn,unii-cz3t9t146k,chembl10188,n-alpha-ethylbenzyl-3-hydroxy-2-phenylquinoline-4-carboxamide,3-hydroxy-2-phenyl-n-1s-1-phenylpropyl-4-quinolinecarboxamide,3-hydroxy-2-phenyl-n-1s-1-phenylpropyl quinoline-4-carboxamide,n-s-alpha-ethylbenzyl-3-hydroxy-2-phenylcinchoninamide,4-quinolinecarboxamide, 3-hydroxy-2-phenyl-n-1s-1-phenylpropyl,d0k5hi
5311424
3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O
This item is not returnable. View return policy
174636-32-9
C25H22N2O2
382.463
BIAVGWDGIJKWRM-FQEVSTJZSA-N
talnetant,talnetant inn,unii-cz3t9t146k,chembl10188,n-alpha-ethylbenzyl-3-hydroxy-2-phenylquinoline-4-carboxamide,3-hydroxy-2-phenyl-n-1s-1-phenylpropyl-4-quinolinecarboxamide,3-hydroxy-2-phenyl-n-1s-1-phenylpropyl quinoline-4-carboxamide,n-s-alpha-ethylbenzyl-3-hydroxy-2-phenylcinchoninamide,4-quinolinecarboxamide, 3-hydroxy-2-phenyl-n-1s-1-phenylpropyl,d0k5hi
5311424
3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O

Potent, selective non-peptide NK3 antagonist. Brain penetrant

Potent and selective non-peptide NK3 receptor antagonist (Ki values are 1, 144 and >100000 nM for human NK3, NK2 and NK1 receptors respectively). Selective over a panel of >60 receptors, enzymes and ion channels at concentrations of 1 or 10 μM. Inhibits NKB-induced Ca2+ mobilization in vitro (IC50 = 16.6 nM) and inhibits NK3-agonist-induced behavioral responses in vivo. Orally active and brain penetrant.
Quantity 50mg
Formula Weight 382.45
Percent Purity >98%
Chemical Name or Material SB 223412

Recommended Storage : Store at +4°C