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Tocris™ SB 328437

Potent and selective CCR3 antagonist

Manufacturer:  Tocris™ 3650/10

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Catalog No. 36-501-0R


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Disclaimers:

For Research Use Only


Specifications

Description

Potent and selective CCR3 antagonist (IC50 = 4nM). Displays > 2500-fold selectivity over C5aR, LTD4, CCR7, CXCR1 and CXCR2 receptors. Inhibits eotaxin-, eotaxin-2- and MCP-4-induced Ca2+ mobilization (IC50 values are 38, 35 and 20nM respectively) and inhibits eotaxin-, eotaxin-2- and MCP-4-induced eosinophil chemotaxis with similar potencies.
  • Chemical Name: N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester
  • Formula: C21H18N2O5
  • CAS Number: 247580-43-4
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >99
Description & Specifications

Specifications

SB 328437
>99
10mg
SB 328437
378.38
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