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SB 590885, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
405554-55-4
C27H27N5O2
453.546
DPCXEUSDRQOOGZ-UHFFFAOYSA-N
5-2-4-2-dimethylamino ethoxy phenyl-5-4-pyridinyl-1h-imidazol-4-yl-2,3-dihydro-1h-inden-1-one oxime,2-4-4-1e-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine,2-4-4-1z-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine,2-4-4-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine
53239990
N,N-dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine
CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
This item is not returnable. View return policy
405554-55-4
C27H27N5O2
453.546
DPCXEUSDRQOOGZ-UHFFFAOYSA-N
5-2-4-2-dimethylamino ethoxy phenyl-5-4-pyridinyl-1h-imidazol-4-yl-2,3-dihydro-1h-inden-1-one oxime,2-4-4-1e-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine,2-4-4-1z-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine,2-4-4-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine
53239990
N,N-dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine
CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2

Potent B-Raf inhibitor

Potent B-Raf inhibitor (K d = 0.3 nM). Selective for B-Raf against 46 other kinases (K i app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively). Decreases anchorage-independent growth of melanoma cell lines. Inhibits ERK phosphorylation and proliferation in tumor cells expressing B-Raf V600E .
Quantity 50mg
Formula Weight 453.54
Percent Purity >98%
Chemical Name or Material SB 590885

Recommended Storage : Store at -20°C