Tocris™ SB 612111 hydrochloride

Selective NOP receptor antagonist

Manufacturer: Tocris™ 3573/10

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Catalog No. 35-731-0R

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For Research Use Only


    Product Type SB 612111 hydrochloride
    Inhibitors SB 612111 hydrochloride
    Purity >98
    Molecular Weight 454.86
    Quantity 10mg

    Selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109nM for NOP,µ-, κ- and δ-receptors respectively). Antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. Potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model.

    • Chemical Name: 7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol hydrochloride
    • Formula: C24H29Cl2NO.HCl
    • CAS Number: 371980-94-8
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

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