Tocris™ SB 657510

Selective urotensin-II (UT) receptor antagonist

Manufacturer: Tocris™ 3571/50

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Catalog No. 35-715-0R

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For Research Use Only


    Inhibitors SB 657510
    Purity >98
    Molecular Weight 505.81
    Quantity 50mg
    Product Type SB 657510

    Selective urotensin-II (UT) receptor antagonist (Ki values are 61, 17, 30, 65 and 56nM at human, monkey, cat, rat and mouse receptors respectively). Inhibits U-II-induced intracellular Ca2+ mobilization (IC50 = 180nM) and antagonizes the contractile action of U-II in isolated mammalian arteries and aortae (EC50 = 50 - 189nM).

    • Chemical Name: 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide
    • Formula: C19H22BrClN2O5S
    • CAS Number: 474960-44-6
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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