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  8. SB 706375, Tocris Bioscience™

SB 706375, Tocris Bioscience™

Catalog Number p-4816596
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
733734-61-7
C20H22BrF3N2O5S
539.364
BPOWQJYAMDEAFF-CYBMUJFWSA-N
2-bromo-4,5-dimethoxy-n-3-3r-1-methylpyrrolidin-3-yl oxy-4-trifluoromethyl phenyl benzenesulfonamide, d07jdu, r-2-bromo-4,5-dimethoxy-n-3-1-methylpyrrolidin-3-yloxy-4-trifluoromethyl phenyl benzenesulfonamide, 2-bromo-4,5-dimethoxy-n-3-3r-1-methyl-3-pyrrolidinyl oxy-4-trifluoromethyl phenyl benzenesulfonamide, benzenesulfonamide,2-bromo-4,5-dimethoxy-n-3-3r-1-methyl-3-pyrrolidinyl oxy-4-trifluoromethyl phenyl
21023902
2-bromo-4,5-dimethoxy-N-[3-[(3R)-1-methylpyrrolidin-3-yl]oxy-4-(trifluoromethyl)phenyl]benzenesulfonamide
CN1CCC(C1)OC2=C(C=CC(=C2)NS(=O)(=O)C3=C(C=C(C(=C3)OC)OC)Br)C(F)(F)F
This item is not returnable. View return policy
733734-61-7
C20H22BrF3N2O5S
539.364
BPOWQJYAMDEAFF-CYBMUJFWSA-N
2-bromo-4,5-dimethoxy-n-3-3r-1-methylpyrrolidin-3-yl oxy-4-trifluoromethyl phenyl benzenesulfonamide, d07jdu, r-2-bromo-4,5-dimethoxy-n-3-1-methylpyrrolidin-3-yloxy-4-trifluoromethyl phenyl benzenesulfonamide, 2-bromo-4,5-dimethoxy-n-3-3r-1-methyl-3-pyrrolidinyl oxy-4-trifluoromethyl phenyl benzenesulfonamide, benzenesulfonamide,2-bromo-4,5-dimethoxy-n-3-3r-1-methyl-3-pyrrolidinyl oxy-4-trifluoromethyl phenyl
21023902
2-bromo-4,5-dimethoxy-N-[3-[(3R)-1-methylpyrrolidin-3-yl]oxy-4-(trifluoromethyl)phenyl]benzenesulfonamide
CN1CCC(C1)OC2=C(C=CC(=C2)NS(=O)(=O)C3=C(C=C(C(=C3)OC)OC)Br)C(F)(F)F

Description

High affinity, non-peptide UT receptor antagonist

High affinity, non-peptide antagonist of the urotensin-II (UT) receptor. Exhibits high affinity for mammalian UT receptors, including human, mouse and rat (Ki values are 9.3, 19.1 and 20.7 nM respectively, in HEK293 cells expressing recombinant UT receptors). Also inhibits binding of radiolabeled urotensin to endogenous human UT receptors (Ki = 5.4 nM in a whole-cell binding assay). Displays ≥100-fold selectivity for the human UT receptor over 86 different receptors, ion channels, enzymes, transporters and nuclear hormones.
Quantity 10 mg
Formula Weight 539.36
Percent Purity >98%
Chemical Name or Material SB 706375

Safety and Handling

Recommended Storage Store at Room Temperature
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