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SCAMP2 Mouse anti-Human, Clone: OTI3C2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526297

Catalog No. PIMA526297


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Description

Description

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
Specifications

Specifications

SCAMP2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O15127
Secretory carrier-associated membrane protein 2, Secretory carrier membrane protein 2, SCAMP2
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10066
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3C2
Unconjugated
SCAMP2
Liquid
SCAMP2
Full length human recombit protein of SCAMP2 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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