SCD Mouse anti-Human, Mouse, Rat, Clone: CD.E10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527542
DescriptionStearoyl-CoA desaturase (SCD; EC 220.127.116.11) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999); Wang et al., 2005).
|PBS with 0.05% sodium azide; pH 7.2|
|Stearoyl-CoA desaturase-1; SCD1; CD.E10|
|-20° C, Avoid Freeze/Thaw Cycles|
|20249, 246074, 6319|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Full length human recombit protein against SCD1.|
|Human, Mouse, Rat|
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