Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SCN2B Mouse anti-Human, Mouse, Rat, Clone: S395-68, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527665

Catalog No. PIMA527665

Add to cart



Scn2b is a member of voltage-gated sodium channels (NaV) that are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. Scn2b are also expressed at low levels in non-excitable cells, where their physiological role is unclear. Scn2b is crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. In Scn2b, the subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Also, Scn2b interacts with TNR (Tenascin R-precursor) and may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. The protein encoded by the Scn2b gene is the beta 2 subunit of the type II voltage-gated sodium channel. Scn2b protein is involved in cell-cell adhesion and cell migration. Defects in the Scn2b gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. Diseases associated with SCN2B include Atrial Fibrillation, Familial, 14 and Scn2b-Related Familial Atrial Fibrillation.


1 mg/ml
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
O60939, P54900, Q56A07
Sodium channel subunit beta-2, Scn2b, UNQ326/PRO386, Gm183
100 μg
25349, 6327, 72821
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Fusion protein amino acids 1-215 (full-length) of mouse Nav beta2
Protein G
Human, Mouse, Rat
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit