gamma-ENaC Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA551073
SCNN1G Polyclonal Antibody detects endogenous levels of SCNN1G protein.Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2. Apical cell membrane; Multi-pass membrane protein. Phosphorylated on serine and threonine residues. Defects in SCNN1G are a cause of Liddle syndrome. It is an autosomal domit disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel.
|Synthesized peptide derived from the Internal region of human ENaC ENaC G.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|ELISA, Western Blot|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|P51170, Q9WU39, P37091|
|SCNN1G, Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, ENaCG, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG|
|-20° C, Avoid Freeze/Thaw Cycles|
|20278, 24768, 6340|
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