SDHB Mouse anti-Human, Clone: OTI1E4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808115

Catalog No. 50-166-8637

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Specifications

• Antigen: SDHB
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: SDHB
• Gene Alias: CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6390
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI1E4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P21912
• Gene Symbols: SDHB
• Immunogen: Full length human recombit protein of human SDHB produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1