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SDZ NKT 343, Tocris Bioscience™

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Quantity:
10mg
This item is not returnable. View return policy
180046-99-5
C33H33N5O5
579.657
PCVSIMQAFWRUEC-JDXGNMNLSA-N
sdz nkt 343,sdz-nkt-343,1-2-nitrophenyl amino carbonyl-l-prolyl-n-methyl-3-2-naphthalenyl-n-phenylmethyl-l-alaninamide,sdznkt343,d04rup,s-n2-s-1-benzyl methyl amino-3-naphthalen-2-yl-1-oxopropan-2-yl-n1-2-nitrophenyl pyrrolidine-1,2-dicarboxamide,s-pyrrolidine-1,2-dicarboxylic acid 2-s-1-benzyl-methyl-carbamoyl-2-naphthalen-2-yl-ethyl-amide 1-2-nitro-phenyl-amide
9851211
(2S)-2-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-(2-nitrophenyl)pyrrolidine-1,2-dicarboxamide
CN(CC1=CC=CC=C1)C(=O)C(CC2=CC3=CC=CC=C3C=C2)NC(=O)C4CCCN4C(=O)NC5=CC=CC=C5[N+](=O)[O-]
This item is not returnable. View return policy
180046-99-5
C33H33N5O5
579.657
PCVSIMQAFWRUEC-JDXGNMNLSA-N
sdz nkt 343,sdz-nkt-343,1-2-nitrophenyl amino carbonyl-l-prolyl-n-methyl-3-2-naphthalenyl-n-phenylmethyl-l-alaninamide,sdznkt343,d04rup,s-n2-s-1-benzyl methyl amino-3-naphthalen-2-yl-1-oxopropan-2-yl-n1-2-nitrophenyl pyrrolidine-1,2-dicarboxamide,s-pyrrolidine-1,2-dicarboxylic acid 2-s-1-benzyl-methyl-carbamoyl-2-naphthalen-2-yl-ethyl-amide 1-2-nitro-phenyl-amide
9851211
(2S)-2-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-(2-nitrophenyl)pyrrolidine-1,2-dicarboxamide
CN(CC1=CC=CC=C1)C(=O)C(CC2=CC3=CC=CC=C3C=C2)NC(=O)C4CCCN4C(=O)NC5=CC=CC=C5[N+](=O)[O-]

Highly selective, human NK1 antagonist

Highly selective human tachykinin NK 1 receptor antagonist (IC 50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK 2 and NK 3 receptors. Potently antagonizes SP-induced Ca 2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo.
Quantity 10mg
Formula Weight 579.65
Percent Purity >98%
Chemical Name or Material SDZ NKT 343

Recommended Storage : Store at +4°C