SEC14L1 Mouse anti-Human, Clone: OTI3A6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527082
DescriptionMay play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608).
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|PRELID4A, SEC14L, SEC14-like protein 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of SEC14L1 produced in HEK293T cell|
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