Invitrogen™ SEC61A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115879

Catalog No. PIPA5115879

Description

Antibody detects endogenous levels of total SEC61A.

The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.

Specifications

• Antigen: SEC61A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEC61A1
• Gene Alias: AA408394; AA410007; homologue to sec61; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; protein transport protein Sec61 subunit alpha isoform 1; protein transport protein Sec61 subunit alpha isoform 1; protein transport protein Sec61 subunit alpha; SEC61; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha subunit homolog; sec61 alpha-1; sec61 homolog; sec61 homologue; SEC61 translocon alpha 1 subunit; SEC61 translocon subunit alpha 1; SEC61, alpha subunit; SEC61A; SEC61A1; transport protein sec61 alpha subunit
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29927, 53421, 80843
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P61619, P61620, P61621
• Gene Symbols: SEC61A1
• Immunogen: A synthesized peptide derived from human SEC61A1(Accession P61619), corresponding to amino acid residues S443-F476.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov