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SecinH3, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
853625-60-2
C24H20N4O4S
460.508
QPGYAMIHXLCFTJ-UHFFFAOYSA-N
secinh3, cytohesins inhibitor secinh3, secinh3 and cytohesins inhibitor secinh3, n-4-5-1,3-benzodioxol-5-yl-3-methoxy-1h-1,2,4-triazol-1-yl phenyl-2-phenylthio acetamide, secin h3, n-4-5-benzo d 1,3 dioxol-5-yl-3-methoxy-1h-1,2,4-triazol-1-yl phenyl-2-phenylthio acetamide, n-4-5-1,3-benzodioxol-5-yl-3-methoxy-1,2,4-triazol-1-yl phenyl-2-phenylsulfanylacetamide, n-4-5-2h-1,3-benzodioxol-5-yl-3-methoxy-1h-1,2,4-triazol-1-yl phenyl-2-phenylsulfanyl acetamide
1029232
N-[4-[5-(1,3-benzodioxol-5-yl)-3-methoxy-1,2,4-triazol-1-yl]phenyl]-2-phenylsulfanylacetamide
COC1=NN(C(=N1)C2=CC3=C(C=C2)OCO3)C4=CC=C(C=C4)NC(=O)CSC5=CC=CC=C5
This item is not returnable. View return policy
853625-60-2
C24H20N4O4S
460.508
QPGYAMIHXLCFTJ-UHFFFAOYSA-N
secinh3, cytohesins inhibitor secinh3, secinh3 and cytohesins inhibitor secinh3, n-4-5-1,3-benzodioxol-5-yl-3-methoxy-1h-1,2,4-triazol-1-yl phenyl-2-phenylthio acetamide, secin h3, n-4-5-benzo d 1,3 dioxol-5-yl-3-methoxy-1h-1,2,4-triazol-1-yl phenyl-2-phenylthio acetamide, n-4-5-1,3-benzodioxol-5-yl-3-methoxy-1,2,4-triazol-1-yl phenyl-2-phenylsulfanylacetamide, n-4-5-2h-1,3-benzodioxol-5-yl-3-methoxy-1h-1,2,4-triazol-1-yl phenyl-2-phenylsulfanyl acetamide
1029232
N-[4-[5-(1,3-benzodioxol-5-yl)-3-methoxy-1,2,4-triazol-1-yl]phenyl]-2-phenylsulfanylacetamide
COC1=NN(C(=N1)C2=CC3=C(C=C2)OCO3)C4=CC=C(C=C4)NC(=O)CSC5=CC=CC=C5

Description

Sec7-specific GEF inhibitor; selective for cytohesin family

Sec7-specific GEF inhibitor that displays selectivity for small GEFs of the cytohesin family (IC50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, yGea2-S7 and hEFA6-S7 respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein (IRS) phosphorylation.
Quantity 10 mg
Formula Weight 460.5
Percent Purity >99%
Chemical Name or Material ARF GTPase Inhibitors

Safety and Handling

Recommended Storage : Store at +4°C