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Serpin A3/alpha 1-Antichymotrypsin Antibody (AACT/1451), Alexa Fluor™ 532, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP254339AF532
Description
Serpin A3/alpha 1-Antichymotrypsin Monoclonal specifically detects Serpin A3/alpha 1-Antichymotrypsin in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
Serpin A3/alpha 1-Antichymotrypsin | |
Monoclonal | |
Alexa Fluor 532 | |
50 mM sodium borate with 0.05% sodium azide | |
SERPINA3 | |
Recombinant human Serpin A3/alpha 1-Antichymotrypsin protein fragment (around aa 49-187) (exact sequence is proprietary) (Uniprot: P01011) | |
Primary | |
It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity. | |
Store at 4°C in the dark. |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
AACT/1451 | |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin | |
AACTMGC88254, ACTGIG25, alpha-1-antichymotrypsin, antitrypsin), member 3, Cell growth-inhibiting gene 24/25 protein, growth-inhibiting protein 24, growth-inhibiting protein 25, member 3, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 3, Serpin A3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) | |
Mouse | |
0.1 mL | |
12 | |
Human | |
IgG1 |
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