Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SERPINB1 Mouse anti-Canine, Human, Non-human primate, Clone: OTI1D1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526361

Catalog No. PIMA526361


Add to cart

Description

Description

The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The monocyte/neutrophil elastase inhibitor gene, SERPINB1, belongs to the Ov-serpin family (ovalbumin-related serpins). Human SerpinB1, also designated monocyte/neutrophil elastase inhibitor (M/NEI) or leukocyte elastase inhibitor (LEI), is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), cathepsin-G and proteinase-3. There are four homologous genes in mouse designated SerpinB1a, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1. The three protein-coding genes share significant sequence identity, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1.
Specifications

Specifications

SERPINB1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P30740
EI, ELANH2, LEI, M/NEI, MNEI, PI2, PI-2, anti-elastase, leukocyte elastase inhibitor, monocyte/neutrophil elastase inhibitor, peptidase inhibitor 2, protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1, serpin
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1992, 488191, 707471
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1D1
Unconjugated
SERPINB1
Liquid
SERPINB1
Human recombit protein fragment corresponding to amino acids 77-306 of SERPINB1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Non-human primate
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit