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SESN1 Rabbit anti-Human, Rat, Polyclonal, Invitrogen

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550132

Catalog No. PA550132


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Description

Description

The antibody detects endogenous levels of total SESN1 protein.

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specifications

Specifications

SESN1
Polyclonal
Unconjugated
SESN1
Liquid
SESN1
Synthesized peptide derived from internal of human SESN1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9Y6P5
PA26, SEST1
Rabbit
IgG
100 μL
-20°C
Primary
27244, 294518
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