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SESN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 216681AP

Catalog No. 50-173-3545


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Description

Description

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specifications

Specifications

SESN1
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P58006, Q9Y6P5
p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1
Rabbit
IgG
150 μL
-20°C
Primary
140742, 27244, 294518
Western Blot
Unconjugated
SESN1
Liquid
SESN1
SESN1 Fusion Protein Ag16462
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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