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SET8 / PR-SET7 Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen SET8 / PR-SET7
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3075 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61010
10 μL
Each for $135.30
Add to cart
 
50-199-3074 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61009
100 μL
Each for $534.00
Add to cart
 
Description

Description

SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. It is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.
Specifications

Specifications

Polyclonal
Primary
SET8 / PR-SET7
Unconjugated
SDS
Product Certifications
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