SETD8 Mouse anti-Human, Clone: OTI5E5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808217

Catalog No. 50-166-8698

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Histone methyltransferase that specifically monomethylates ′Lys-20′ of histone H4. H4 ′Lys-20′ monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintece of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.

Specifications

• Antigen: SETD8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: KMT5A
• Gene Alias: PR-Set7, SET07, SET8, SETD8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387893
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI5E5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9NQR1
• Gene Symbols: KMT5A
• Immunogen: Full length human recombit protein of human SETD8 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1