SETD8 Mouse anti-Human, Clone: OTI5E5, lyophilized, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene CF808217

Catalog No. 50-166-8698

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Histone methyltransferase that specifically monomethylates  ft.Lys-20 ft. of histone H4. H4  ft.Lys-20 ft. monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintece of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.

Specifications

• Antigen: SETD8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: KMT5A
• Format: Lyophilized
• Gene Symbols: KMT5A
• Immunogen: Full length human recombit protein of human SETD8 produced in E.coli.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Western Blot
• Clone: OTI5E5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9NQR1
• Gene Alias: PR-Set7, SET07, SET8, SETD8
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μg
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 387893