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SEZ6L Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550757

Catalog No. PA550757


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Description

Description

The antibody detects endogenous levels of total SEZ6L protein.

SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Specifications

Specifications

SEZ6L
Polyclonal
Unconjugated
SEZ6L
Liquid
SEZ6L
Synthetic peptide corresponding to residues near the C terminal of human seizure related 6 homolog (mouse)-like
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin)
2 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9BYH1, Q6P1D5
KIAA0927
Rabbit
IgG
100 μL
-20°C
Primary
23544, 56747
Documents
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