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Tocris™ SGC 707

Potent and selective allosteric inhibitor of PRMT3

Manufacturer:  Tocris™ 5367/10

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Catalog No. 53-671-0

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For Research Use Only



Potent allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 31nM). Inhibits PRMT3-mediated methyltransferase activity in vitro. Displays >100-fold selectivity against 31 other methyltransferases and 250 other non-epigenetic targets.
  • Chemical Name: 1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea
  • Formula: C16H18N4O2
  • Solubility: Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
  • Purity: >98
Description & Specifications


SGC 707
SGC 707
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