Tocris™ SGC 707

Potent and selective allosteric inhibitor of PRMT3

Manufacturer: Tocris™ 5367/10

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Catalog No. 53-671-0

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For Research Use Only


    Product Type SGC 707
    Inhibitors SGC 707
    Purity >98
    Molecular Weight 298.34
    Quantity 10mg

    Potent allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 31nM). Inhibits PRMT3-mediated methyltransferase activity in vitro. Displays >100-fold selectivity against 31 other methyltransferases and 250 other non-epigenetic targets.

    • Chemical Name: 1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea
    • Formula: C16H18N4O2
    • Solubility: Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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