Invitrogen™ SGCE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA592400

Catalog No. PIPA592400

Description

Immunogen sequence: MQLPRWWELG DPCAWTGQGR GTRRMSPATT GTFLLTVYSI FSKVHSDRNV YPSAGVLFVH VLEREYFKGE FPPYPKPGEI SNDPITFNTN LMGYPDRPGW LRYIQRTPYS DGVLYGSPTA ENVGKPTIIE ITAYNRRTFE TARHNLIINI MSAEDFPLPY QAEFFIKNMN VEEMLASEVL GDFLGAVKNV WQPERLNAIN ITSALDRGGR VPLPINDLKE GVYVMVGADV PFSSCLREVE NPQNQLRCSQ EMEPVITCDK KFRTQFYIDW CKISLVDKTK QVSTYQEVIR GEGILPDGGE YKPPSDSLKS RDYYTDF; Positive Samples: SW620, A-549; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Golgi apparatus, Single-pass membrane protein, cytoskeleton, dendrite, sarcolemma.

This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SGCE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGCE
• Gene Alias: dystonia 11, myoclonic; DYT11; EMBL:AAO37579.1, ECO:0000312; EMBL:AAO37579.1}; Epsilon sarcoglycan; Epsilon SG; Epsilon-sarcoglycan; epsilon-sarcoglycan {ECO:0000312; epsilon-SG; epsilon-SG {ECO:0000250; ESG; e-SG; RGD:1303201}; sarcoglycan; sarcoglycan epsilon; sarcoglycan, epsilon; SGCE; sgce {ECO:0000312; UniProtKB:O43556}; UNQ433/PRO840
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20392, 8910
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43556, O70258
• Gene Symbols: SGCE
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human SGCE (NP_0039101).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG