Invitrogen™ SGEF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109410

Catalog No. PIPA5109410

Description

Immunogen sequence: ICQKTPKDSP KYEVCKRALK EVSKLVRLCN EGARKMERTE MMYTINSQLE FKIKPFPLVS SSRWLVKRGE LTAYVEDTVL FSRRTSKQQV YFFLFNDVLI ITKKKSEESY NVNDYSLRDQ LLVESCDNEE LNSSPGKNSS TMLYSRQSSA SHLFTLTVLS NHANEKVEML LGAETQSERA RWITALGHSS GKPPADRTSL TQVEIVRSFT AKQPDELSLQ VADVVLIYQR VSDGWYEGER LRDGERGWFP MECAKEITCQ ATIDKNVERM GRLLGLETNV.

Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

Specifications

• Antigen: SGEF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGEF26
• Gene Alias: 4631416L12Rik; 8430436L14Rik; AI303572; ARHGEF26; AW491953; CSGEF; HMFN1864; RGD1562559; Rho guanine nucleotide exchange factor (GEF) 26; Rho guanine nucleotide exchange factor 26; SGEF; SH3 domain-containing guanine exchange factor; Src homology 3 domain-containing guanine nucleotide exchange factor; testicular tissue protein Li 171
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26084, 310460, 622434
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.75 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q96DR7
• Gene Symbols: ARHGEF26
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG