Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SHANK2 Mouse anti-Human, Mouse, Rat, Clone: S23b-6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527634

Catalog No. PIMA527634


Add to cart

Description

Description

This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants.
Specifications

Specifications

SHANK2
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Q80Z38, Q9QX74, Q9UPX8
Shank2, PROSAP1, cortactin binding protein 1, KIAA1022, AUTS17, CortBP1, Proline-rich synapse-associated protein 1, SH3 and multiple ankyrin repeat domains protein 2, Cortactin-binding protein 1, proline-rich synapse associated protein 1, SPANK-3, GKAP/SAPAP interacting protein, SHANK, cortactin SH3 domain-binding protein, ProSAP1, CORTBP1CTTNBP1, SH3 and multiple ankyrin repeat domains 2
Mouse
IgG1
100 μg
-20°C
Primary
171093, 210274, 22941
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
S23b-6
Unconjugated
SHANK2
Liquid
SHANK2
Fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (SH3 and multiple ankyrin repeat domains protein 2)
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit