Invitrogen™ SHB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562088

Catalog No. PIPA562088

Description

Immunogen sequence: TACGGKKLLN KCAASAAEES GAGKKDKVTI ADDYSDPFDA KNDLKSKAGK GESAGYM Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.

The SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain-containing proteins to tyrosinephosphorylated sites, an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function. Shb (SH2 domain-containing adapter protein b), Shd (SH2 domain-containing adapter protein d), She (SH2 domain-containing adapter protein e) and Shf(SH2 domain-containing adapter protein f) are SH2 domain-containing proteins that play various roles throughout the cell.

Specifications

• Antigen: SHB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SHB
• Gene Alias: bA3J10.2; BC028832; SH2 domain containing adaptor protein B; SH2 domain-containing adapter protein B; Shb; SHB (Src homology 2 domain containing) adaptor protein B; SHB adaptor protein (a Src homology 2 protein); Src homology 2 domain containing adaptor protein B; src homology 2 domain-containing transforming protein B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6461
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15464
• Gene Symbols: SHB
• Immunogen: Recombinant protein corresponding to Human SHB. Recombinant protein control fragment (Product #RP-99509).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG