Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
SHISA4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 221971AP150UL
Description
SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.Specifications
SHISA4 | |
Polyclonal | |
Unconjugated | |
SHISA4 | |
C1orf40, hShisa4, Protein shisa 4, SHISA4, TMEM58, Transmembrane protein 58 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
149345, 77552 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Western Blot | |
0.39 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8CA71, Q96DD7 | |
SHISA4 | |
SHISA4 Fusion Protein Ag17357 | |
150 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Provide Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?
Provide Content Correction