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SHISA4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 221971AP

Catalog No. 50-173-3765


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Description

Description

SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
Specifications

Specifications

SHISA4
0.39 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8CA71, Q96DD7
C1orf40, hShisa4, Protein shisa 4, SHISA4, TMEM58, Transmembrane protein 58
Rabbit
IgG
150 μL
-20°C
Primary
149345, 77552
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
SHISA4
Liquid
SHISA4
SHISA4 Fusion Protein Ag17357
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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