SHMT2 Mouse anti-Human, Clone: OTI1E6, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF808814
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOMammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.
|Full length human recombit protein of human SHMT2 produced in E.coli.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|GLYA, HEL-S-51e, SHMT|
|-20° C, Avoid Freeze/Thaw Cycles|
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