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SHMT2 Mouse anti-Human, Clone: OTI1E6, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF808814

Catalog No. 50-166-9096


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.
Specifications

Specifications

SHMT2
Monoclonal
Unconjugated
SHMT2
Lyophilized
SHMT2
Full length human recombit protein of human SHMT2 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin)
OTI1E6
PBS with 8% trehalose and no preservative; pH 7.3
P34897
GLYA, HEL-S-51e, SHMT
Mouse
IgG2a
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6472
SDS
Documents
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