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SHMT2 Mouse anti-Human, Clone: OTI1E6, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA808814

Encompass_Preferred

Catalog No. 50-168-2389


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Description

Description

Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.
Specifications

Specifications

SHMT2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P34897
SHMT2
Full length human recombit protein of human SHMT2 produced in E.coli.
100 μL
Primary
Human
Antibody
IgG2a
Immunohistochemistry (Paraffin)
OTI1E6
Unconjugated
SHMT2
GLYA, HEL-S-51e, SHMT
Mouse
Affinity Chromatography
RUO
6472
-20° C, Avoid Freeze/Thaw Cycles
Liquid
SDS
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