Invitrogen™ SI-CLP Monoclonal Antibody (1C11)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA549028

Catalog No. FERMA549028

Description

In vivo, the monoclonal antibody 1C11 recognizes SI-CLP in the cellular fraction of bronchoalveolar lavage specimens obtained from patients with chronic inflammatory disorders of the respiratory tract and in peripheral-blood leukocytes (PBLs) from these patients as well as healthy donors.

SI-CLP detects human Stabilin-interacting chitinase like protein (SI-CLP), a novel member of the Glyco-18-domain containing protein family. SI-CLP is a secretory protein which is up-regulated in response to interleukin-4 and dexamethasone in activated macrophages. SI-CLP is also expressed by T- and B-lymphocytes, and by cells of monocytic and epithelial origin. SI-CLP is the ligand for stabilin-1, an intracellular sorting receptor which sorts SI-CLP into late endosomes and secretory lysosomes in activated macrophages.

Specifications

• Antigen: SI-CLP
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: Q9BWS9
• Gene Symbols: CHID1
• Immunogen: Amino acids 24 to 73 fragment GST-fusion protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot, Immunocytochemistry
• Clone: 1C11
• Conjugate: Unconjugated
• Gene: CHID1
• Gene Alias: 3110023E09Rik; AI841869; CHID1; chitinase domain containing 1; chitinase domain-containing protein 1; FLJ42707; GL008; MGC3234; PSEC0104; SB139; SICLP; SI-CLP; stabilin-1 interacting chitinase-like protein; stabilin-1-interacting chitinase-like protein
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 66005
• Content And Storage: 4°C
• Form: Liquid