Potent neuronal nicotinic ACh receptor agonist (EC50 values are 1.8, 5, 9 and 23nM for α4β2, α2β4, α4β4 and α3β4 receptors respectively). Improves cognitive function in a MPTP-induced model of Parkinson's Disease in vivo.
Chemical Name: 3-Ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine maleate salt
CAS Number: 192231-16-6
Solubility: Soluble to 100mM in water and to 50mM in DMSO
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