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Tocris™ SIB 1508Y maleate

Potent agonist of alpha4beta2, alpha2beta4, alpha4beta4 and alpha3beta4 nACh receptors

Manufacturer:  Tocris™ 4766/50

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Catalog No. 47-665-0

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For Research Use Only



Potent neuronal nicotinic ACh receptor agonist (EC50 values are 1.8, 5, 9 and 23nM for α4β2, α2β4, α4β4 and α3β4 receptors respectively). Improves cognitive function in a MPTP-induced model of Parkinson's Disease in vivo.
  • Chemical Name: 3-Ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine maleate salt
  • Formula: C12H14N2.C4H4O4
  • CAS Number: 192231-16-6
  • Solubility: Soluble to 100mM in water and to 50mM in DMSO
  • Purity: >98
Description & Specifications


SIB 1508Y maleate
SIB 1508Y maleate
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