Tocris™ SIB 1508Y maleate

Potent agonist of alpha4beta2, alpha2beta4, alpha4beta4 and alpha3beta4 nACh receptors

Manufacturer: Tocris™ 4766/10

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Catalog No. 47-661-0

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For Research Use Only


    Product Type SIB 1508Y maleate
    Inhibitors SIB 1508Y maleate
    Purity >98
    Molecular Weight 302.33
    Quantity 10mg

    Potent neuronal nicotinic ACh receptor agonist (EC50 values are 1.8, 5, 9 and 23nM for α4β2, α2β4, α4β4 and α3β4 receptors respectively). Improves cognitive function in a MPTP-induced model of Parkinson's Disease in vivo.

    • Chemical Name: 3-Ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine maleate salt
    • Formula: C12H14N2.C4H4O4
    • CAS Number: 192231-16-6
    • Solubility: Soluble to 100mM in water and to 50mM in DMSO
    • Purity: >98

  • Description & Specifications

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