Tocris™ SIB 1757

Highly selective mGlu5 antagonist

Manufacturer: Tocris™ 1215/10

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Catalog No. 12-151-0

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For Research Use Only


    Product Type SIB 1757
    Inhibitors SIB 1757
    Molecular Weight 213.24
    Quantity 10mg

    A highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4µM at hmGlu5 compared with > 30µM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.

    • Chemical Name: 6-Methyl-2-(phenylazo)-3-pyridinol
    • Formula: C12H11N3O
    • CAS Number: 31993-01-8
    • Solubility: Soluble to 100mM in DMSO

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