Tocris SIB 1757
Highly selective mGlu5 antagonist
Manufacturer: Tocris 1215/10
DescriptionA highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4µM at hmGlu5 compared with > 30µM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
- Chemical Name: 6-Methyl-2-(phenylazo)-3-pyridinol
- Formula: C12H11N3O
- CAS Number: 31993-01-8
- Solubility: Soluble to 100mM in DMSO
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