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Tocris Bioscience™ SIB 1893

mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors

$137.00 - $575.00

Specifications

Product Type SIB 1893
Molecular Weight (g/mol) 195.26
Inhibitors SIB 1893
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
12-141-0
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Tocris Bioscience™
1214/10
10 mg
Each for $137.00
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12-145-0R
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Tocris Bioscience™
1214/50
50 mg
Each for $575.00
Add to cart
 
Description

Description

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.
Specifications

Specifications

SIB 1893
195.26
SIB 1893
SDS
Product Certifications

For Research Use Only

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