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Tocris Bioscience™ SIB 1893

mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors

Specifications

Product Type SIB 1893
Molecular Weight (g/mol) 195.26
Inhibitors SIB 1893
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
12-141-0
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Tocris Bioscience™
1214/10
10 mg N/A N/A N/A
Description

Description

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.
Specifications

Specifications

SIB 1893
195.26
SIB 1893
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