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Tocris Bioscience™ SIB 1893
mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors
Specifications
| Product Type | SIB 1893 |
|---|---|
| Molecular Weight (g/mol) | 195.26 |
| Inhibitors | SIB 1893 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
12-141-0
|
Tocris Bioscience™
1214/10 |
10 mg | N/A | N/A | N/A | ||||
Description
A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.Specifications
| SIB 1893 | |
| 195.26 | |
| SIB 1893 |
For Research Use Only
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