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Siglec-2/CD22 Rabbit anti-Human, Cynomolgus Monkey, Rhesus Macaque, Clone: hL22 (Epratuzumab), Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275189

Catalog No. NBP275189

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Siglec-2/CD22 Monoclonal antibody specifically detects Siglec-2/CD22 in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Immunoprecipitation, Block/Neutralize.


hL22 (Epratuzumab)
Flow Cytometry 1:100 - 1:1000, Immunoprecipitation 1:10 - 1:500, Block/Neutralize
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
Protein A purified
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
Blocking Assay, Flow Cytometry, Immunoprecipitation
PBS with 0.02% Proclin 300
B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, CD22 antigenMGC130020, CD22 molecule, sialic acid binding Ig-like lectin 2, Sialic acid-binding Ig-like lectin 2, SIGLEC-2, SIGLEC2FLJ22814, T-cell surface antigen Leu-14
IgG Kappa
0.2 mg
Cynomolgus Monkey, Human, Rhesus Macaque
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