SIKE Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549286
Predicted to react with rat based on sequence homology.Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
|PBS with 0.09% sodium azide|
|Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.|
|Antigen affinity chromatography|
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