Invitrogen™ SIM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568590

Catalog No. PIPA568590

Description

This target displays homology in the following species: Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 91%; Pig: 93%; Rabbit: 92%; Rat: 100%.

This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

Specifications

• Antigen: SIM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIM2
• Gene Alias: BHLHE15; Class E basic helix-loop-helix protein 15; HMC13F06; HMC29C01; mSIM; SIM; SIM bHLH transcription factor 2; SIM transcription factor; sim2; single-minded 2; single-minded family bHLH transcription factor 2; single-minded homolog 2; single-minded homolog 2 (Drosophila); single-minded protein; transcription factor SIM2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6493
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q14190
• Gene Symbols: SIM2
• Immunogen: synthetic peptide directed towards the middle region of human SIM2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov