Invitrogen™ SIM2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142641

Catalog No. PIPA5142641

Description

Additional Information: This antibody is expected to recognize all reported isoforms (NP_005060.1; NP_033664.2). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

Specifications

• Antigen: SIM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIM2
• Gene Alias: BHLHE15; Class E basic helix-loop-helix protein 15; HMC13F06; HMC29C01; mSIM; SIM; SIM bHLH transcription factor 2; SIM transcription factor; sim2; single-minded 2; single-minded family bHLH transcription factor 2; single-minded homolog 2; single-minded homolog 2 (Drosophila); single-minded protein; transcription factor SIM2
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 20465
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q61079
• Gene Symbols: SIM2
• Immunogen: Peptide with sequence C-SDLLYTPSYS.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG