Sino Biological BMPR1A, Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Arg 152) of human ALK3 (NP_004320.2) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus
Manufacturer: Invitrogen 10446H03H50
DescriptionBone Morphogenetic Protein Receptor, Type IA (BMPR1A), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
- Activity: Measured by its ability to inhibit BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells, the ED50 for this effect is typically 0.1-0.3µg/mL in the presence of 50ng/mL of recombinant human BMP4
- Formulation: 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
- Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible
|Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories|
|≥85% by SDS-PAGE|
|Store at -5° to -30°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.|
|Bone morphogenetic protein receptor, type IA|
|ACVRLK3, ALK3, CD292, BMPR1A|
|Growth Factors & Receptors|
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