Sino Biological CD63 Recombinant Human Protein, His Tag
This recombinant human protein is expressed from a DNA sequence encoding the second the extracellular domain (Ala 103-Val 203) of human CD63 (P08962-1) fused to both a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus
Manufacturer: Invitrogen 11271H08H250
DescriptionCluster of Differentiation 63 (CD63) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.Background: CD63, is a multipass membrane protein which belongs to the tetraspanin (TM4SF) family. Tetraspanins participate in a variety of cellular processes, like cell activation, adhesion, differentiation and tumour invasion. CD63/Tspan-30 is expressed in melanoma and appears to be involved in regulation of motility and adhesion of melanoma cells. CD63/Tspan-30 is associated with early stages of melanoma tumor progression. It may play a role in growth regulation. Lack of expression of CD63 in platelets has been observed in a patient with Hermansky-Pudlak syndrome (HPS), which is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects.
- Activity: This recombinant protein has not been tested
- Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80
- Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible
|Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories|
|≥90% by SDS-PAGE|
|Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.|
|LAMP-3, ME491, MLA1, OMA81H, TSPAN30|
|5 x 50μg|
|Truncated/Recombinant/Cell Surface Protein|
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