Sino Biological™ FGFR1 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag Non-distribution product as customer accommodation.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 285) of human FGFR1 (NP_075594.1) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Manufacturer: Invitrogen 10616H03H250

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Catalog No. 10-616-H03HL

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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


    Specifications

    For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
    Format Lyophilized
    Gene ID (Entrez) 2260
    Molecular Weight 57.5kDa
    Purity ≥85% by SDS-PAGE
    Quantity 5 x 50μg
    Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
    Structural Form Truncated/Recombinant
    Protein Subtype Receptor Tyrosine Kinases|Growth Factor Receptors
    Endotoxin Concentration <1 EU/μg
    Gene Alias FGFR1, BFGFR, CD331, CEK, FGFBR, FLG, FLJ99988, FLT2, HBGFR, KAL2, N-SAM
    Common Name Fibroblast growth factor receptor 1
    Gene Symbol FGFR1
    Protein Tag His Tag/IgG1 Fc Tag
    Validated Application Assay Standard
    Protein Family Growth Factors & Receptors
    Expression System Mammalian
    KinaseFamily FGF Receptor Kinase Family

    Fibroblast growth factor receptor 1 (FGFR1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

    • Activity: Measured by its ability to inhibit FGF1-dependent proliferation of BALB/c 3T3 mouse fibroblasts, the ED50 for this effect is typically 2-4ng/mL
    • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80
    • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

    Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.

  • Description & Specifications

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