Sino Biological™ IL6ST Recombinant Mouse Protein, hIgG1-Fc.His Tag Non-distribution product as customer accommodation.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 617) of mouse IL6ST (NP_034690.3) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Manufacturer: Invitrogen 50135M03H5

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Catalog No. 50-135-M03H5

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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


    Specifications

    For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
    Format Lyophilized
    Gene ID (Entrez) 16195
    Molecular Weight 94.7kDa
    Purity ≥90% by SDS-PAGE
    Quantity 5μg
    Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
    Structural Form Truncated/Recombinant
    Protein Subtype Interleukins|Cytokine Receptors
    Endotoxin Concentration <1 EU/μg
    Gene Alias IL6ST,5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130
    Common Name Interleukin 6 signal transducer
    Gene Symbol IL6ST
    Protein Tag His Tag/IgG1 Fc Tag
    Validated Application Assay Standard
    Protein Family Cytokines & Receptors/CD Proteins
    Expression System Mammalian

    Interleukin 6 signal transducer (IL6ST), recombinant mouse protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.

    • Activity: Measured by its ability to inhibit the IL6RA enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168); the ED50 for this effect is typically 0.05-0.2µg/mL in the presence of 50ng/mL recombinant human IL6sR and 100ng/mL recombinant human IL6
    • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80
    • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

    Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.

  • Description & Specifications

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