SIPA1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA588447

Catalog No. PIPA588447

Description

Immunogen sequence: ESGRPRRSFS ELYTLSLQEP SRRGAPDPVQ DEVQGVTLLP TTKQLLHLCL QDGGSPPGPG DLAEERTEFL HSQNSLSPRS SLSDEAPVLP NTTPDLLLAT TAKPSVPSAD SETPLTQDRP GSPSGSEDKG NPAPELRASF LPRTLSLRNS ISRIMSEAGS GTLEDEWQAI SEIASTCNTI LESLSREGQP IPESGDPKGT PKSDAEPEPG NLSEKVSHLE SMLRKLQEDL QKEKADRAAL EEEVRSLRHN NRRLQAESES AATRLLLASK QLGSPTADLA; Positive Samples: Raji, K-562, HeLa, LO2, Mouse spleen; Cellular Location: Cytoplasm, Endomembrane system, Nucleus, Peripheral membrane protein, perinuclear region

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Specifications

• Antigen: SIPA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIPA1
• Gene Symbols: Sipa1
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 763-1042 of human SIPA1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 1.71 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P46062, Q96FS4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20469, 6494
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid