Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SIPA1L1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 250861AP

Catalog No. 50-173-4715


Add to cart

Description

Description

Signal-induced proliferation associated-like protein 1 (SIPA1L1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.
Specifications

Specifications

SIPA1L1
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O43166, Q8C0T5
E6 targeted protein 1, E6TP1, KIAA0440, SIPA1 like protein 1, SIPA1L1
Rabbit
IgG
150 μL
-20°C
Primary
217692, 26037
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
SIPA1L1
Liquid
Sipa1l1
SIPA1L1 Fusion Protein Ag18900
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit