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SIPA1L2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA565007

Catalog No. PIPA565007


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Description

Description

Immunogen sequence: SSPSNQSSSSD PGPGGSGPWR PQVGYDGCQS PLLLEHQGSG PLECDGARER EDTMEASRHP ETKWHGPPSK VLGSYKERAL QKDGSCKDSP NKLSHIGDKS CSSH Highest antigen sequence identity to the following orthologs - mouse 86%, rat 87%.

Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
Specifications

Specifications

SIPA1L2
Polyclonal
Unconjugated
SIPA1L2
Liquid
SIPA1L2
Recombit Human SIPA1L2
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence
0.05 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9P2F8
SPAL2; SIPA1-like protein 2; SPA-1-like 2; signal-induced proliferation-associated 1-like protein 2
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
57568
SDS
Documents
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