Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SIRT1 Mouse anti-Human, Clone: 2G1/F7, Active Motif™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen SIRT1
Conjugate Unconjugated
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2687 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39354
10 μg
Each for $135.30
Add to cart
 
50-199-2686 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39353
200 μg
Each for $534.00
Add to cart
 
Description

Description

NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression. It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).
Specifications

Specifications

Monoclonal
Primary
SIRT1
Unconjugated
SDS
Product Certifications
Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit