SIRT5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 151221AP
DescriptionSIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q68FX9, Q8K2C6, Q9NXA8|
|SIR2 like protein 5, SIR2L5, SIRT5|
|23408, 306840, 68346|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|SIRT5 Fusion Protein Ag7195|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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