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SIRT5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 151221AP

Catalog No. 50-172-9998


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Description

Description

SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Specifications

Specifications

SIRT5
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q68FX9, Q8K2C6, Q9NXA8
SIR2 like protein 5, SIR2L5, SIRT5
Rabbit
IgG
150 μL
-20°C
Primary
23408, 306840, 68346
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
SIRT5
Liquid
Sirt5
SIRT5 Fusion Protein Ag7195
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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