BioVision Inc SIRT6 Inhibitor Screening Kit (Fluorometric): SIRT6 Inhibitor Screening Kit: High-Throughput Suitable Fluorometric Assay Kit to Screen SIRT6 Inhibitors. Rapid, Simple & Sensitive. Includes Inhibitor Control, Nicotinamide. 100 Assays.
Manufacturer: BioVision Inc K323100
SIRT6 Inhibitor Screening Kit (Fluorometric): SIRT6 or Sirtuin 6 proteins are a class of proteins that possess either histone deacetylase or mono-ribosyltransferase activity. SIRT6 is a nuclear sirtuin that has been associated with aging, cellular protection, sugar metabolism and certain types of cancer. In BioVision's Sirtuin 6 inhibitor screening Kit, Sirtuin 6 deacetylates the substrate, followed by cleavage of the deacetylated substrate to release the fluorescent group, which is detected fluorometrically at Ex/Em = 395/541 nm. In the presence of SIRT inhibitor, deacetylation is impeded, preventing cleavage of the substrate and release of the fluorescent group. This kit provides a rapid, simple, sensitive, and reliable test, which is suitable for high-throughput screening of SIRT6 inhibitors. Inhibitor control (Nicotinamide) is included to compare the efficacy of the test inhibitors. BioVision charges an Ice pack and Insulated Container fee of $25.00 for each order.