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SIRT6 Mouse anti-Human, Clone: OTI1G3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525716

Catalog No. PIMA525716


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Description

Description

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.
Specifications

Specifications

SIRT6
Monoclonal
1.0 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N6T7
2810449N18Rik;AI043036;Mono ADP ribosyltransferase sirtuin 6;NAD-dependent protein deacetylase sirtuin-6;Regulatory protein SIR2 homolog 6;Regulatory protein SIR2 homolog;SIR2 like 6;SIR2 like protein 6;Sir2 related protein type 6;SIR2-like protein 6;SIR2
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
51548
Immunocytochemistry, Immunofluorescence, Western Blot
OTI1G3
Unconjugated
SIRT6
Liquid
SIRT6
Human recombit protein fragment corresponding to amino acids 88-352 of SIRT6 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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